Scientific & Technical Support: Toxicology
Regulatory toxicology is the study of the adverse effects of chemicals on humans
and other living organisms, such as plants, animals, fungi and insects.
Toxicology studies are often required by regulatory agencies to determine the
adverse effects of a chemical product, and to assure it meets agency standards
for safety.
TSG’s team of board certified toxicologists are highly skilled in the design,
evaluation and interpretation of all toxicological studies, including:
▲Acute,
subchronic and chronic toxicity
▲Developmental and reproductive
toxicity
▲Neurotoxicity and carcinogenicity
▲Mobility
and
environmental fate
▲Endangered
species and ecosystems
TSG uses this broad range of expertise to provide a
complete range of services including:
▲Mammalian toxicology evaluations
▲Human exposure analysis
▲Human health risk assessments
▲Ecological risk assessment
▲Peer review
In addition, our scientists are proficient in the four components of risk
assessment: hazard identification, dose-response assessment, exposure
assessment and risk characterization. These risk assessments range in scope
from single population and single route of exposure, to combination risk
assessments that include evaluation of potential risks to multiple
populations exposed by multiple routes. We have extensive experience
conducting risk assessments for
pesticide registrations, occupational
exposure and consumer products.
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| Key Contacts | |
 Gary Burin |
 Beth Mileson |
TSG’s consultants are highly knowledgeable of the registration requirements for disinfectants regulated by both PMRA and TPD. TSG provides comprehensive product registration services, from determining data obligations and developing compliant labels, to compiling and submitting the registration application.
The goals of EPA's TSCA IUR program are to collect quality screening-level, exposure-related information on chemical substances in commerce in the United States and to make that information available for use by EPA and the public. The IUR data are used to support risk screening, assessment, priority setting and management activities at EPA and constitute the most comprehensive source of basic information on chemicals in commerce available to EPA.
TSG has offices throughout North America and Europe, including Sacramento, CA, Washington, DC, Canada, United Kingdom, Spain and Slovenia. Through these locations and our affiliates, TSG works with companies in 36 countries worldwide including China, Japan, Australia, New Zealand and Latin America.
REACH (Registration, Evaluation, Authorization and restriction of Chemicals) is an EU Regulation that came into effect on June 1st, 2007, imposing strict guidelines on the manufacture or import of chemicals, preparations and articles in or to the EU.
Drinking Water and Toxic Enforcement Act of 1986, better known as Proposition 65, was approved by voters to address the growing concerns about exposure to toxic chemicals. Proposition 65 requires California to publish a list of chemicals, updated at least once a year, known to cause cancer, birth defects or other reproductive harm. Proposition 65 also requires California businesses to post notification about significant amounts of chemicals in the products they sell, in their homes or workplaces, or that are released into the environment.